Jordane Dimidschstein

This study uses CRISPR activation to upregulate SCN1A in PV interneurons, improving survival and reducing seizures in Dravet syndrome models.

The paper shows that eGlyRs in hippocampal interneurons regulate network activity through developmental and evolutionary conserved mechanisms.

The paper identifies a novel inhibitory interneuron subtype in the dentate gyrus that selectively regulates mossy cell function and shows this pattern is evolutionarily conserved across species.

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

The paper validates and characterizes viral vectors for targeting GABAergic and parvalbumin interneurons in marmoset primary visual cortex, showing high specificity and efficiency.

The paper shows that opioids suppress inhibition in hippocampal PV-INs but not neocortex across species and development, highlighting conserved and divergent roles in neural circuits.

The paper shows that cortical reactivations predict future sensory responses and representational drift in mice.

The paper analyzes single-nucleus RNA sequencing data from marmoset brain cells to show that neuronal identity is more influenced by developmental origin than functional class.

This study shows that Nova proteins, through activity-dependent alternative splicing, are essential for the maturation and connectivity of somatostatin interneurons.

This study investigates how ventral hippocampus inputs engage inhibitory interneurons in the prefrontal cortex, revealing specific roles for CCK+ interneurons and endocannabinoid modulation in feed-forward inhibition.

The paper profiles interneurons in primates and rodents to identify evolutionary innovations in brain cell types and their molecular features.

The paper identifies enhancers for targeting specific neuronal subtypes across species and demonstrates their utility in circuit manipulation.