Nayuta Yakushiji‐Kaminatsui

This study identifies SPIN1 as a chromatin regulator that selectively represses young transposable elements in mouse embryonic stem cells through histone modification recognition.

The paper shows that the shh limb enhancer MFCS1 is active in patterned limb regeneration in tadpoles but not in hypomorphic regeneration in froglets, suggesting epigenetic regulation is key.

This study shows that Ring1, a Polycomb group protein, regulates ventral identity in the mouse telencephalon by suppressing BMP and Wnt signaling to allow Shh expression.

This study identifies two mammalian-specific enhancers upstream of the HoxC gene cluster that regulate Hoxc gene expression in ectodermal organs like hair and nails.

The paper investigates how chromatin domain structure affects Hox gene regulation, showing that enhancer activity and silencing marks are influenced by TAD boundaries and Polycomb complex recruitment.

The paper compares bimodal HoxD gene regulation in chicken and mouse limb development, finding conserved mechanisms with species-specific differences in enhancer activity and TAD boundaries.