Todd Lamitina

This study identifies RAD23A and USP13 as modifier genes that enhance TDP-43 solubility and reduce neuronal toxicity in ALS models.

This paper shows that stress signals from peripheral tissues can influence neuronal behavior in C. elegans by modulating lysosomal function and neurophysiology.

This paper identifies SPOP as a conserved regulator of C9orf72 dipeptide toxicity in C. elegans and mammalian neurons, showing SPOP inhibition protects against toxicity.

This study evaluates the toxicity of CAG repeat-derived RAN polypeptides in C. elegans, finding that polyLeu is toxic independently of polyQ.