Beatriz Dias

This study shows SMURF2 inhibits autophagy against Mycobacterium tuberculosis in macrophages, suggesting it as a potential target for tuberculosis therapy.

This study identifies CMPK2 as a host factor that restricts Mycobacterium tuberculosis replication in human macrophages and alters gene expression related to innate immunity.

This study identifies SNX5 as a regulator of MHC-II antigen presentation during Mtb infection, linking endosomal sorting to immune responses against intracellular pathogens.

This study shows that airflow constraints can suppress tuberculosis transmission in guinea pigs, even under conditions that would otherwise allow transmission.

This study identifies USP15 as a negative regulator of autophagy and macrophage immunity to Mycobacterium tuberculosis, showing that its inhibition reduces bacterial burden.

This study develops a humanized lung-on-a-chip model to study early immune responses to Mycobacterium fortuitum infection, revealing cytokine and protease inhibitor upregulation.