Samuel Álvarez-Arguedas

This study shows SMURF2 inhibits autophagy against Mycobacterium tuberculosis in macrophages, suggesting it as a potential target for tuberculosis therapy.

This study generates a Pglyrp1-Cre mouse to target M cells and related lineages in mucosal tissues, showing tissue-specific promoter activity and challenges in achieving M cell-specific targeting.

This study identifies SNX5 as a regulator of MHC-II antigen presentation during Mtb infection, linking endosomal sorting to immune responses against intracellular pathogens.

This study uses snRNA-seq to identify molecular features of human airway microfold cells and discovers a novel epithelial cell type with an interferon-stimulated gene signature.