Author

Carsten E. Seyfert

German Center for Infection ResearchORCID 0000-0001-7433-5290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander WagneriD· 1 shared Andreas M. KanyiD· 1 shared Christoph DehioiD· 1 shared Claudia Fink‐Straube· 1 shared Jens ReinersiD· 1 shared Markus Huber· 1 shared Rolf MülleriD· 1 shared Sander H. J. SmitsiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Alexander WagnerORCID

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2 papers

Recent·Most cited

BioengineeringJournal of Biological EngineeringPeer-reviewedNov 12, 2024

Thermo-amplifier circuit in probiotic E. coli for stringently temperature-controlled release of a novel antibiotic

Sourik Dey, Carsten E. Seyfert, Claudia Fink‐Straube…·Shrikrishnan Sankaran

The paper develops a thermo-amplifier circuit in probiotic E. coli to control the release of darobactin, a peptide antibiotic, at 40°C while maintaining low leakiness at 37°C.

11 citations

E. coliproteomics

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MicrobiologybioRxivPreprintMar 25, 2024

Full-length structure of the host targeted bacterial effector Bep1 reveals a novel structural domain conserved in FIC effector proteins from Bartonella

Markus Huber, Alexander Wagner, Jens Reiners…·Christoph Dehio

The paper determines the crystal structure of Bep1, revealing a novel FIC-OB-BAS(BID) domain arrangement and its role in T4SS translocation.

DOI 10.1101/2024.03.25.586700

protein structureexperimental assay

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