Author

Emiel B. J. ten Buren

SanquinORCID 0000-0001-7450-4752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Achim TreschiD· 1 shared Alessandro SinopoliiD· 1 shared Alvin HsuiD· 1 shared Amélie WiederkehriD· 1 shared André LieberiD· 1 shared Anna CamusiD· 1 shared Chang Long LiiD· 1 shared Christopher DivsalariD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Achim TreschORCID

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2 papers

Recent·Most cited

CD117 epitope-shielded hematopoietic stem cell transplantation with toxin-free conditioning and in vivo selection ameliorates β-thalassemia model

Romina Marone, Rosalba Lepore, Kiriaki Paschoudi, Jessica Zuin, Alessandro Sinopoli, Anna Camus, Thomas Burgold, Ewelina Magdalena Bartoszek, Diego Calabrese, Mylene Toranelli, Julia Rositzka, Manuel Rhiel, Geoffroy Andrieux, Chang Long Li, Alvin Hsu, , Lukas T. Jeker

This paper demonstrates a method using CD117-blocking antibody and epitope-engineered HSPCs to treat β-thalassemia without myeloablative conditioning.

bioRxiv · Jul 8, 2026 · PreprintBioengineering

Group size planning of breedings of gene-modified animals

Vladislava Milchevskaya, Philippe Bugnon, Emiel B. J. ten Buren, Frank Brand, Achim Tresch, Thorsten Buch

The paper develops an R package and website to optimize breeding design for gene-modified animals, minimizing animal use while ensuring successful outcomes.

bioRxiv · Sep 17, 2021 · PreprintBioinformatics