Jesús Reiné

This study shows that targeting the CCR2 inflammatory pathway reduces severe disease and pulmonary inflammation in a mouse model of SARS-CoV2 infection.

This study shows MEG3 is upregulated in DM1 and exhibits nuclear retention, with antisense conjugates correcting MEG3 levels in mice.

This paper introduces CRISPR MiRAGE, a miRNA-sensing guide RNA system that enables tissue-specific gene editing by modulating CRISPR activity based on miRNA signatures.