Molecular BiologybioRxivPreprint
Dysregulated MEG3 in Myotonic Dystrophy 1: nuclear retention, pathological role, and therapeutic correction by antisense conjugates.
David Seoane-Miraz, Jessica Stoodley, Natalia Galindo Riera…·Miguel A. Varela
This study shows MEG3 is upregulated in DM1 and exhibits nuclear retention, with antisense conjugates correcting MEG3 levels in mice.