Simon George

This study maps DNA replication origins in Trypanosoma brucei using stranded short nascent strand sequencing, revealing their sequence, structural, and chromatin features.

The paper identifies co-translational interactions between R2TP and client proteins, revealing a mechanism called co-translational chaperone channeling that facilitates early assembly of protein complexes.

This study identifies adaptive genetic variation in black-chinned tilapia along a salinity gradient, highlighting osmoregulation and immune-related pathways.

This paper shows that TAK-981 activates NK cells against AML by inducing IFN-I secretion, enhancing their cytotoxicity and cytokine production.

This study identifies MdBRC1 and MdFT2 interaction as a molecular switch regulating bud break timing in apple trees, with implications for climate resilience.

This study shows that inhibiting SUV4-20H enzymes enhances the effectiveness of TOP2 poisons in prostate cancer by increasing DNA damage and impairing repair mechanisms.

The paper shows that co-translational interactions sort β-catenin mRNAs into distinct polysome populations with different localizations and protein fates.

The paper examines the transcriptional responses of Spodoptera frugiperda tissues to Steinernema carpocapsae infestation, identifying gene expression changes and potential immune effectors acquired via horizontal gene transfer.