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The paper uses unmapped reads from whole-exome sequencing data in the UK BioBank to construct features and identify 21 novel genetic loci associated with immune-related traits.

This study shows female mice clear MRSA from the gut faster than males, relying on gut microbiota and Th17 cells, while ovariectomy reduces this resistance.

This study uses patient-derived intestinal organoids to predict individual clinical responsiveness to tofacitinib in ulcerative colitis by assessing drug sensitivity and MATE1 expression.