Satish Babu Moparthi

This study identifies HCK signaling as a driver of long-distance ECM degradation in macrophages through endo-exocytosis coupling involving MMPs and cathepsins.

This study identifies Piezo1 as a regulator of focal and reticular adhesions, showing its role in EGFR clathrin-mediated endocytosis on stiff substrates.

This study shows vimentin enables efficient collective cell migration by converting polarized cell movement into coordinated group motion during wound healing.

This study shows HRS forms 2D condensates that drive flat clathrin lattice assembly on endosomes, with cholesterol enhancing this process.

This study uses optogenetic tools to reveal distinct functional roles of SRC and HCK kinases in macrophages, despite their redundancy.

The paper investigates how the actin-spectrin scaffold in axons regulates clathrin-mediated endocytosis, finding that spectrin clearings restrict pit formation and endocytic activity.