Author

Matthew Denman Smith

Edinburgh Cancer ResearchORCID 0000-0001-7603-8628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alain J. Kemp· 1 shared Alex von KriegsheimiD· 1 shared Carla Salomo-ColliD· 1 shared Damian J. MoleiD· 1 shared Hywel Dunn-DaviesiD· 1 shared Jennifer P. MortoniD· 1 shared Jocelyn HolkhamiD· 1 shared Katie Winnington-Ingram· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alain J. Kemp

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1 paper

Recent·Most cited

Cancer BiologyDevelopmental CellPeer-reviewedAug 15, 2025

Dysproteostasis primes pancreatic epithelial state changes in KRAS-mediated oncogenesis

Carla Salomo-Coll, Marisa Di Monaco, Jocelyn Holkham…·Simon Wilkinson

This study shows that proteostatic failure in ER-phagy, driven by Kras, leads to protein aggregates that prime acinar-ductal metaplasia and pancreatic cancer.

7 citationstop 4%

mouseproteomics

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