Hervé Chneiweiss

Human cortico-vascular assembloids reveal a CELF2-AHNAK-dependent switch from neuronal to endothelial tropism in glioblastoma cells

This study develops a human cortico-endothelial assembloid model to investigate glioblastoma cell tropism, identifying CELF2 and AHNAK as key regulators of neuronal versus endothelial invasion.

Knowledge and misconceptions of the French population regarding medical genetics: a survey of 3,000 respondents

This study surveys 3,000 French individuals to assess their knowledge and misconceptions about medical genetics, revealing limited understanding and significant gaps in awareness of genetic testing limitations and legal frameworks.

A unique malignant cell type per patient tumor is encoded in each cancer cell transcriptome.

The paper identifies tumor-specific malignant cell types encoded across the transcriptome, independent of patient origin or computational biases.

Nicotinamide Metabolism Reprogramming Drives Reversible Senescence of Glioblastoma Cells

This study shows nicotinamide induces reversible senescence in glioblastoma cells by reprogramming metabolism and reducing SOX2, with senescent cells retaining tumor-forming ability.

Immune Cells Infiltration of Patient Derived Glioblastoma Cells spheroids in Acoustic Levitation in Bulk Acoustic Wave devices

The paper describes an acoustofluidic device for creating 3D tumoroids from patient-derived glioblastoma cells and shows immune cell infiltration in these tumoroids.