Léa Bellenger

This study identifies RIPOR2 as a downstream target of the RAS/ERK pathway that promotes multinucleation in melanoma cells, contributing to aneuploidy and tumor progression.

The paper identifies tumor-specific malignant cell types encoded across the transcriptome, independent of patient origin or computational biases.

The paper identifies an immature neuroblast population with plasticity and molecular switches in splicing regulators during neurogenesis.

The paper identifies a non-redundant OPC subpopulation marked by C1ql1 that is essential for myelination during postnatal development.

The paper uses single-cell RNA-sequencing to study fibroblast diversity and developmental trajectories in chicken limb connective tissue, showing a shift from positional signaling to lineage diversification.

The paper introduces a Galaxy-based suite for scRNA-seq analysis, offering workflows, training resources, and tools for preprocessing, normalization, and clustering across 10x and alternative platforms.

The paper identifies a fibroblast-to-myoblast conversion driven by BMP signalling at the muscle-tendon interface during limb development.