Author

Grant M. Calder

University of York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Paul Martin KayeiD· 3 shared Alastair DroopiD· 2 shared Helen M. AshwiniD· 2 shared Karen HoggiD· 2 shared Lesley Gilbert· 2 shared Peter J O’TooleiD· 2 shared Sally R. JamesiD· 2 shared Shoumit DeyiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Paul Martin KayeORCID

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Author profile →

5 papers

Recent·Most cited

Dynamic diffusion analysis of the yeast plasma membrane using Airyscan based microscopic techniques

Martha S. C. Xelhuantzi, Alex Roof, Blythe Wright, Katherine M. Paine, Amy Milburn, Grant M. Calder, Nia J. Bryant, Peter J O’Toole, Ines Hahn, Chris MacDonald

This study compares FCS and FRAP techniques to measure diffusion in yeast plasma membrane proteins, revealing discrepancies in Sso2 diffusion due to subdomain localization.

bioRxiv · Jul 21, 2026 · PreprintCell Biology

Ontogeny-independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis

Shoumit Dey, Jianhua Cao, Benjamin Balluff, Gaia Mazza, Helen M. Ashwin, Lesley Gilbert, Sally R. James, Adam Dowle, Grant M. Calder, Nidhi Sharma Dey, Peter J O’Toole, Ron M. A. Heeren, Paul Martin Kaye

The paper uses multimodal imaging and single-cell transcriptomics to identify LPCAT2-mediated membrane remodeling in granuloma macrophages during visceral leishmaniasis.

Communications Biology · Mar 20, 2026Peer-reviewedImmunology

Spatial profiling of central nervous system cellular markers in murine breast cancer to brain metastases

Karen Hogg, Grant M. Calder, Alastair Droop, Ming Yang, Anna Simon, Mark Jeremy Hunt, Paul Martin Kaye, Miles A. Whittington, Sangeeta Chawla, William J. Brackenbury

The paper uses spatial profiling to analyze cellular marker changes in murine brain metastases, identifying upregulated immune markers and downregulated neuronal markers.

Wellcome Open Research · Mar 18, 2026Peer-reviewedNeuroscience

Bi-directional highways and super-seeder tissues underpin parasite dissemination in experimental visceral leishmaniasis.

Ciara F. Loughrey, Juliana B. T. Carnielli, Shoumit Dey, Helen M. Ashwin, Sally R. James, Lesley Gilbert, Samantha L. Donninger, Alastair Droop, Grant M. Calder, Karen Hogg, Jon W. Pitchford, Jeremy Charles Mottram, Paul Martin Kaye

This study maps parasite dissemination patterns in visceral leishmaniasis using a barcoded library and ecological analysis, revealing bi-directional highways and super-seeder tissues.

bioRxiv · Dec 30, 2025 · PreprintMicrobiology

Non-canonical inflammasome drives intrinsic anti-microbial responses in human Natural Killer (NK) cells.

Nathan Georges François Leborgne, Jadie Acklam, Alexander J. Hogg, Zarema Albakova, Karen G. Hogg, Kim S. Robinson, Grant M. Calder, Arnel Junior Villamin, Callum Robson, Freya Pealing, Matthew A. Care, Monika Gońka, James M. Fox, James Iremonger, Frances Elizabeth Pearson, , Dave Boucher

This study identifies a non-canonical inflammasome in human NK cells that mediates anti-microbial responses against Salmonella without canonical inflammasome components.

bioRxiv · Oct 20, 2025 · PreprintImmunology