Author

Jaeun Jung

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

Su‐Jin HeoiD· 4 shared Ellen Y. ZhangiD· 3 shared Bat‐Ider TumenbayariD· 2 shared Inkyung JungiD· 2 shared Sang Hyun LeeiD· 2 shared Se-Hwan Lee· 2 shared Tyler E. BlanchiD· 2 shared Claudia LoebeliD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBioengineering

Su‐Jin HeoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Engineering a Biomimetic Multiphasic Suture Anchor System for Enhanced Rotator Cuff Enthesis Regeneration

Zizhao Li, Se-Hwan Lee, Lin Xu, Marina I. Santos, Ruqiang Lu, Ellen Y. Zhang, DongHwa Kim, Bat‐Ider Tumenbayar, Tyler E. Blanch, Jaeun Jung, Jayden Shin, Yongho Bae, Richard T. Tran, Thomas P. Schaer, Su‐Jin Heo

This paper develops a biomimetic scaffold system to enhance rotator cuff enthesis regeneration by replicating native tissue properties and integrating with conventional suture anchors.

Science Advances · Aug 21, 2026Peer-reviewedBioengineering

Hyperactive BMP and Mechanosignaling Remodel Chromatin to Drive Aberrant Osteogenesis in FOP

Ellen Y. Zhang, Douglas W. Roberts, Sang Hyun Lee, Bat‐Ider Tumenbayar, Jaeun Jung, Loreilys Mejias Rivera, Inkyung Jung, Robert L. Mauck, Eileen Malko Shore, Su‐Jin Heo

This study shows that the Acvr1R206H mutation in FOP remodels chromatin through BMP-SMAD and Rho/ROCK signaling, driving aberrant osteogenesis, and identifies reversible chromatin changes as a therapeutic target.

Journal of Bone and Mineral Research · Jun 5, 2026Peer-reviewedBioengineering

Reprogramming Dedifferentiation Regulatory Networks Preserves Human Chondrocyte Phenotypes

Ellen Y. Zhang, Sang Hyun Lee, Yu‐Chung Liu, Yuna Heo, Hannah Hyun-Sook Kim, D K Kim, Tyler E. Blanch, Jaeun Jung, Claudia Loebel, Melike Lakadamyali, Robert Mauck, Inkyung Jung, Su‐Jin Heo

This study identifies chromatin stability as critical for preserving chondrocyte function during expansion and shows that Fludarabine maintains phenotype by stabilizing chromatin and reducing STAT1 activity.

bioRxiv · May 13, 2026 · PreprintBioengineering

Genetic liability to meniscus degeneration and its comorbidity patterns: a phenome-wide association study in the UK Biobank

Donggi Augustine Lee, Yonghyun Nam, Jaehyun Joo, Se-Hwan Lee, Jaeun Jung, Su‐Jin Heo, Dokyoon Kim

This study identifies genetic risk factors for meniscus degeneration and shows they are linked to various systemic conditions through a phenome-wide association study.

medRxiv · Sep 23, 2025 · PreprintGenetic & Genomic Medicine