Author

Prashant Singh Chauhan

University of South Bohemia in České BudějoviceORCID 0000-0001-7752-5380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1

Frequent Co-Authors

Ondřej GahuraiD· 4 shared Alena Zı́kováiD· 3 shared Jan Riha· 3 shared Jonathan E. Wong· 3 shared Ingrid Škodová‐SverákováiD· 2 shared Tomáš PánekiD· 2 shared Alexandra ListiD· 1 shared Alexey AmuntsiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMolecular Biology

Ondřej GahuraORCID

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Author profile →

4 papers

Recent·Most cited

A pan-eukaryotic analysis of mitochondrial ribosomes uncovers major evolutionary transitions

Tomáš Pánek, Jan Riha, Pia Corre, Eliška Zadrobílková, Harshini Vummadi, Arsh Suri, Prashant Singh Chauhan, Jonathan E. Wong, Kira Senk, Anton S. Petrov, Victor Tobiasson, Ondřej Gahura

This study analyzes mitoribosome protein composition across 85 eukaryotes to uncover evolutionary transitions and update nomenclature.

bioRxiv · Oct 10, 2026 · PreprintEvolutionary Biology

A p32 family RNA editing factor acts in mitochondrial ribosome biogenesis

Prashant Singh Chauhan, Ingrid Škodová‐Sveráková, Jonathan E. Wong, Jan Riha, Julie DEDKOVÁ, Anna Lena Huber, Lukas Müller, Evgeny S. Gerasimov, Alena Zı́ková, Vyacheslav Yurchenko, Ondřej Gahura

The paper identifies p22, a p32 family member, as essential for mitochondrial ribosome biogenesis in Trypanosoma brucei, revealing its dual role in RNA editing and mitoribosome assembly.

bioRxiv · Aug 4, 2026 · PreprintMolecular Biology

Distinct roles of three trypanosomal Oxa1 insertases in biogenesis of mitochondrial membrane complexes

Jonathan E. Wong, Ingrid Škodová‐Sveráková, Jan Riha, Prashant Singh Chauhan, Alexandra List, Verena DANZINGER, Alena Zı́ková, Ondřej Gahura

This study identifies three Oxa1 paralogs in Trypanosoma brucei and shows they have distinct roles in mitochondrial complex biogenesis.

bioRxiv · Jul 1, 2026 · PreprintBiochemistry

Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome

Yury Zgadzay, Claudio Mirabello, George Wanes, Tomáš Pánek, Prashant Singh Chauhan, Björn Nystedt, Alena Zı́ková, Paul C. Whitford, Ondřej Gahura, Alexey Amunts

The paper investigates the role of Mettl15 and Mettl17 in mitoribosome assembly, revealing their cooperative mechanism in transitioning from early to late stages of small subunit formation.

Structure · Aug 28, 2025Peer-reviewedMolecular Biology