Ondřej Gahura

A pan-eukaryotic analysis of mitochondrial ribosomes uncovers major evolutionary transitions

This study analyzes mitoribosome protein composition across 85 eukaryotes to uncover evolutionary transitions and update nomenclature.

Alternative oxidase in trypanosomatids

This study investigates the evolutionary and functional divergence of alternative oxidase (AOX) and AOX-like (AOX-L) proteins in trypanosomatids, revealing distinct origins and potential regulatory roles.

Interconnections with and within the trypanosomal respiratory chain revealed by complexome profiling

This study uses complexome profiling to reveal new interactions and structural insights into the mitochondrial respiratory chain of Trypanosoma brucei.

A p32 family RNA editing factor acts in mitochondrial ribosome biogenesis

The paper identifies p22, a p32 family member, as essential for mitochondrial ribosome biogenesis in Trypanosoma brucei, revealing its dual role in RNA editing and mitoribosome assembly.

Distinct roles of three trypanosomal Oxa1 insertases in biogenesis of mitochondrial membrane complexes

This study identifies three Oxa1 paralogs in Trypanosoma brucei and shows they have distinct roles in mitochondrial complex biogenesis.

Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome

The paper investigates the role of Mettl15 and Mettl17 in mitoribosome assembly, revealing their cooperative mechanism in transitioning from early to late stages of small subunit formation.

An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases

The paper reports cryo-EM structures of the ATP synthase dimer from Trypanosoma brucei, identifying an ancestral subunit-g/e module critical for oligomerization.