Björn Nystedt

A generalisable framework to inject distance information into Alphafold-like structure predictors

This paper introduces a method to inject distance information into AlphaFold-like structure predictors to improve structure prediction accuracy.

Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome

The paper investigates the role of Mettl15 and Mettl17 in mitoribosome assembly, revealing their cooperative mechanism in transitioning from early to late stages of small subunit formation.

Unmasking AlphaFold: integration of experiments and predictions in multimeric complexes

This study introduces AF_unmasked, a method that integrates experimental data with AlphaFold predictions to improve the accuracy of large protein complex structures.

dgram2dmap: Extraction, visualisation and formatting of distance constraints from AlphaFold distograms

dgram2dmap converts AlphaFold distograms into distance maps for visualization and downstream analysis.

GenErode: a bioinformatics pipeline to investigate genome erosion in endangered and extinct species

GenErode provides a pipeline to analyze genomic erosion by comparing ancient and modern whole-genome re-sequencing data, producing standardized erosion indices.

Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants

Sarek provides a portable and reproducible workflow for analyzing germline and somatic variants from whole-genome sequencing data.

SweGen: A whole-genome map of genetic variability in a cross-section of the Swedish population

SweGen provides a high-quality whole-genome map of genetic variation in the Swedish population, useful for clinical genetics and association studies.