Alexey Amunts

Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome

The paper investigates the role of Mettl15 and Mettl17 in mitoribosome assembly, revealing their cooperative mechanism in transitioning from early to late stages of small subunit formation.

Structure of Photosystem I with SOD reveals coupling between energy conversion and oxidative stress protection

The paper reports the structure of the PSI-SOD supercomplex from Chromera velia, showing how energy conversion and oxidative stress protection are directly coupled.

The mitochondrial methylation potential gates mitoribosome assembly

The paper shows that mitochondrial SAM is essential for processing mitochondrial ribosomal RNA precursors and ribosome assembly.

Improved model building for cryo-EM maps using local attention and 3D rotary position embedding

CryFold improves de novo model building for cryo-EM maps using local attention and 3D rotary position embedding, producing more complete models and reducing resolution requirements.

Structure of the II2-III2-IV2 mitochondrial supercomplex from the parasite Perkinsus marinus

This study determines the structure of a unique II2-III2-IV2 mitochondrial supercomplex from Perkinsus marinus using cryo-EM, revealing novel subunit arrangements and functional features.

dgram2dmap: Extraction, visualisation and formatting of distance constraints from AlphaFold distograms

dgram2dmap converts AlphaFold distograms into distance maps for visualization and downstream analysis.

Structural basis of streptomycin off-target binding to human mitoribosome

This paper reports the 2.23-[A] resolution structure of the human mitoribosomal small subunit bound to streptomycin, revealing new insights into its off-target interactions.

An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases

The paper reports cryo-EM structures of the ATP synthase dimer from Trypanosoma brucei, identifying an ancestral subunit-g/e module critical for oligomerization.