Muneef Ayyash

This study identifies signaling pathways that enable the expansion of human naive pluripotent stem cells in defined conditions and highlights differences between mouse and human naive pluripotency.

This paper maps high-resolution epigenetic and biosynthetic changes during reprogramming of fibroblasts to iPSCs, identifying two gene modules regulated by different mechanisms.

This paper reviews recent advances in understanding the molecular mechanisms and signaling pathways that regulate pluripotent stem cell states in vitro and their reprogramming in somatic cells across species.