Author

Érika de Carvalho

Gulbenkian Institute for Molecular MedicineORCID 0000-0001-7909-6970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Abdulbasit AminiD· 2 shared Colin AdrainiD· 2 shared Emma BurbridgeiD· 2 shared Marina BadenesiD· 2 shared Pedro FaíscaiD· 2 shared Pedro Manuel Dias Neto DomingosiD· 2 shared Camila MarianoiD· 1 shared Catarina J GaspariD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Abdulbasit AminORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A critical role for the ER Membrane Complex (EMC) in lipid droplet homeostasis

Érika de Carvalho, Abdulbasit Amin, Richard LiIttle, Karina Serafim da Silva, Catarina J Gaspar, Marina Badenes, Emma Burbridge, Tiago Paixão, Maria João Amorim, Pedro Faísca, Román Fischer, Iolanda Vendrell, Darragh Patrick O'Brien, Kvido Střı́šovský, John C. Christianson, , Colin Adrain

This study shows that the EMC3 subunit is critical for lipid droplet homeostasis in mice and Drosophila, with loss of EMC3 causing triglyceride storage defects and reduced FITM2 levels.

bioRxiv · Mar 10, 2025 · PreprintBiochemistry

The ADAM17 sheddase complex regulator iTAP modulates inflammation, epithelial repair, and tumor growth

Marina Badenes, Emma Burbridge, Ioanna Oikonomidi, Abdulbasit Amin, Érika de Carvalho, Lindsay Kosack, Camila Mariano, Pedro Manuel Dias Neto Domingos, Pedro Faísca, Colin Adrain

This study shows that iTAP regulates ADAM17 activity, affecting inflammation, epithelial repair, and tumor growth in mice without causing widespread ADAM17 loss effects.

Life Science Alliance · Jan 31, 2023Peer-reviewedMolecular Biology