Author

Nicolas-Frédéric Lipp

University of California San DiegoORCID 0000-0001-7963-7415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1

Frequent Co-Authors

Itay BudiniD· 3 shared Adrian M. WongiD· 2 shared Aurélie LaguerreiD· 1 shared Christian M. MetalloiD· 1 shared Elida KocharianiD· 1 shared Grace H. McGregoriD· 1 shared Hyesoo KimiD· 1 shared Israel Juarez-ContrerasiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

Itay BudinORCID

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3 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedMar 16, 2026

Transport of sphingolipids by yeast Npc2 supports phase separation of the vacuole membrane

Hyesoo Kim, Nicolas-Frédéric Lipp, Israel Juarez-Contreras…·Itay Budin

The paper identifies Npc2's role in sphingolipid transport to the yeast vacuole, showing it supports membrane phase separation during micro-lipophagy.

2 citationstop 4%

yeastproteomics

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Cell BiologyCell chemical biologyPeer-reviewedJan 1, 2026

1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

Yi-Ting Tsai, Nicolas-Frédéric Lipp, Olivia Seidel…·Itay Budin

This study investigates how 1-deoxysphingolipids affect membrane properties and cargo trafficking in the early secretory pathway by analyzing their subcellular distribution and effects on ER membrane fluidity and ERES.

7 citationstop 1%

humanexperimental assay

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Evolutionary BiologybioRxivPreprintMay 16, 2025

A eukaryotic-like phospholipid transfer protein conserved in Asgard archaea

Nicolas-Frédéric Lipp, Elida Kocharian, Itay Budin

The paper identifies a phospholipid transporter in Asgard archaea with structural and functional similarities to eukaryotic LTPs, suggesting lipid transport mechanisms predate eukaryogenesis.

1 citation

Arabidopsisproteomics

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