Author

Michael Costigan

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Clifford J. WoolfiD· 2 shared Adelheid WeidingeriD· 1 shared Alban LatrémolièreiD· 1 shared Alexander J. DaviesiD· 1 shared Alexandra LatiniiD· 1 shared Alexandra Wolf· 1 shared Allison M BarryiD· 1 shared Andrey V. Koslov· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Clifford J. WoolfORCID

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Author profile →

3 papers

Recent·Most cited

NKG2D receptor ligands are cell surface biomarkers for injured murine and human nociceptive sensory neurons

Shuaiwei Wang, Allison M Barry, Yoon Kyung Lee, Naomi Young, Sang Wook Shim, Xinying Wang, Hyeongcheol Kim, Laura Stirling-Barros, Rafael González‐Cano, Michael Costigan, Georgios Baskozos, Simon Rinaldi, David Bennett, Seog Bae Oh, Alexander J. Davies

Journal of Neuroinflammation · Dec 29, 2025Peer-reviewedNeuroscience

Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons

Shane J. F. Cronin, Weonjin Yu, Ashley Hale, Simon Licht‐Mayer, Mark J. Crabtree, Joanna A. Korecka, Evgenii O. Tretiakov, Marco Sealey‐Cardona, Máté Somlyay, Masahiro Onji, Meilin An, Jesse D. Fox, Bruna Lenfers Turnes, Carlos Gomez Diaz, Débora da Luz Scheffer, , Josef Martin Penninger

This study demonstrates that BH4 deficiency exacerbates PD-related stressors and that BH4 augmentation protects dopaminergic neurons in multiple models.

bioRxiv · May 8, 2023 · PreprintNeuroscience

Enhanced neuronal regeneration in the CAST/Ei mouse strain is linked to expression of differentiation markers after injury

Véronique Lisi, Bhagat Singh, Michel Giroux, Elmer Guzman, Michio W. Painter, Yung‐Chih Cheng, Eric A. Huebner, Giovanni Coppola, Michael Costigan, Clifford J. Woolf, Kenneth S. Kosik

The paper identifies Ascl1 upregulation and miR-7048-3p downregulation in CAST/Ei mice as factors contributing to enhanced neuronal regeneration after injury.

Cell Reports · Aug 1, 2017Peer-reviewedMolecular Biology