Author

Edyta Rychlicka-Buniowska

Gdańsk Medical UniversityORCID 0000-0001-8050-2489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 4 Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 6 Research Focus:differential expression· 5 Assay:bulk RNA-seq· 4 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:experimental assay· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Hanna DaviesiD· 6 shared Jan Piotr DumanskiiD· 6 shared Martin IngelssoniD· 4 shared Bożena Bruhn‐OlszewskaiD· 3 shared Daniil SarkisyaniD· 3 shared Jonas MattissoniD· 3 shared Magdalena WójcikiD· 3 shared Natalia H. FilipowicziD· 3 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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6 shared papersGenetic & Genomic Medicine

Hanna DaviesORCID

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6 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 5, 2025

Loss of Y chromosome in Alzheimer disease patients co-occurs with clonal hematopoiesis defined by post-zygotic point mutations outside canonical CHIP driver genes

Edyta Rychlicka-Buniowska, Daniil Sarkisyan, Monika Horbacz…·Jan Piotr Dumanski

The paper investigates the relationship between loss of Y chromosome (LOY) and clonal hematopoiesis in Alzheimer's disease patients, finding that LOY drives myeloid clones which may accumulate additional mutations.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineScientific ReportsPeer-reviewedApr 24, 2024

Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases

Magdalena Wójcik, Ulana Juhas, Elyas Mohammadi…·Jan Piotr Dumanski

The paper investigates LOY in TME leukocytes, finding higher LOY frequency in Tregs and its association with immune checkpoint receptor expression.

23 citationstop 4%

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintFeb 7, 2023

Loss of Y is associated with multi-omic changes in immune cells from Alzheimer's disease patients

Marcin Jąkalski, Edyta Rychlicka-Buniowska, Hanna Davies…·Jakub Mieczkowski

The paper identifies multi-omic changes in immune cells from Alzheimer's disease patients with loss of Y, linking LOY to epigenetic and gene expression alterations.

2 citations

humanDNA methylation

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Genetic & Genomic MedicineGenome MedicinePeer-reviewedDec 13, 2022

Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

Bożena Bruhn‐Olszewska, Hanna Davies, Daniil Sarkisyan…·Jan Piotr Dumanski

The paper investigates LOY in leukocytes as a risk factor for severe COVID-19 in men, finding higher LOY levels in critical cases and associations with immune-related outcomes.

30 citations

humanbulk RNA-seq

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GeneticsbioRxivPreprintMay 11, 2019

Intra-individual changes in the frequency of mosaic loss of chromosome Y over time estimated with a new method

Marcus Danielsson, Jonatan Halvardson, Hanna Davies…·Lars Anders Forsberg

The paper introduces a method to estimate intra-individual changes in mosaic loss of chromosome Y (LOY) over time using standardized SNP-array data, showing higher correlation with other methods and significant individual variation.

3 citations

humanwhole-genome sequencing

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GeneticsbioRxivPreprintJan 8, 2019

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

Deborah J. Thompson, Giulio Genovese, Jonatan Halvardson…·John R. B. Perry

The paper identifies genetic determinants of mosaic Y chromosome loss in blood and links it to genomic instability and non-haematological cancer risk.

6 citations

humanbulk RNA-seq

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