Chaoyang Xue

This study develops and evaluates an HK-fbp1-based vaccine platform against Cryptococcus neoformans, showing superior protection compared to HK-H99 in multiple immunization settings.

This study shows that Cdc50, a lipid flippase regulatory subunit in Cryptococcus neoformans, controls membrane lipid homeostasis, extracellular vesicle biogenesis, and macrophage interactions, with loss of Cdc50 increasing phagocytosis and susceptibility to macrophage killing.

This paper develops a SSP-PCR platform for ultrasensitive detection of azole resistance-associated SNPs in Cryptococcus neoformans, demonstrating high specificity and multiplex detection capabilities.

This study identifies Itr4, a novel inositol transceptor in Cryptococcus neoformans, which regulates inositol and glucose metabolism and fungal virulence.

This study identifies Cig1 as an immunogenic antigen in a heat-killed Cryptococcus neoformans vaccine model, showing its role in T cell recruitment and cytokine production.

The paper identifies 40 Cryptococcus neoformans genes associated with human immune response and disease outcomes using clinical and genomic data from Ugandan patients.