Author

Xiaohui Sun

Children's Medical CenterORCID 0000-0001-8218-1885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Collin GilbreathiD· 2 shared Jun Yi Stanley LimiD· 2 shared Kailiang QiaoiD· 2 shared Sihan WuiD· 2 shared Yipeng XieiD· 2 shared Yoon Jung KimiD· 2 shared Huocong HuangiD· 1 shared Qing‐Lin YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Collin GilbreathORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyNature Cell BiologyPeer-reviewedJun 24, 2026

Cis and Trans Regulatory Mechanisms of ecDNA Segregation

Yipeng Xie, Jun Yi Stanley Lim, Wenyue Liu…·Sihan Wu

This study identifies cis and trans regulatory mechanisms governing ecDNA segregation, showing H3K27ac and bromodomain proteins mediate interactions, while inactive Pol II facilitates attachment.

8 citationstop 3%

humanChIP-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 15, 2025

ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment

Kailiang Qiao, Qing‐Lin Yang, Tuo Li…·Sihan Wu

This study shows ecDNA-driven oncogene super-expressors create an immunoevasive tumor microenvironment in PDAC by promoting myCAF expansion and suppressing T cell infiltration.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky