Mario de Bono

The paper identifies PHAC-1 as a regulator of synaptic transmission in C. elegans and shows that DEE70 variants disrupt cholinergic signalling at the neuromuscular junction.

This study shows that impairing one sensory modality in C. elegans enhances another through reprogramming of peptidergic circuits, specifically via the NPR-22 receptor in ADL neurons.

The paper identifies CAMTA as a regulator of calmodulin (CaM) expression in C. elegans and Drosophila, showing it controls CaM levels and affects neuronal excitability and behavior.

The paper identifies MALT1 as a key mediator of IL-17 signaling in C. elegans neurons, showing its role in behavior, immunity, and longevity.

This study shows that long-term neuronal activity in C. elegans URX sensory neurons leads to dendritic branch elaboration, independent of oxygen sensitivity.

The paper shows that egl-1, a BH3-only gene in C. elegans, is transcriptionally regulated by neuronal activity and kinases in adult sensory neurons without inducing apoptosis.

The paper identifies genes that constrain dendrite growth in C. elegans throughout life, revealing a mechanism distinct from developmental growth pathways.

This paper shows that C. elegans changes its response to pheromones based on recent oxygen experience through circuit-level plasticity in the RMG interneurons.