Author

Maria Laura Avantaggiati

Georgetown University Medical CenterORCID 0000-0001-8361-3440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher AlbaneseiD· 2 shared Rami Mosaoa· 2 shared Aditya KavuturuiD· 1 shared Alec T. McIntoshiD· 1 shared Anna Kasprzyk-Pawelec· 1 shared Cecil Han· 1 shared Eric F. GlasgowiD· 1 shared Garrett T. GrahamiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Christopher AlbaneseORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 20, 2025

Tumor intrinsic regulation of PD-L1 and of interferon Type I via an SLC25A1-driven mitochondrial pathway, influences the anti-tumor immune response

Rami Mosaoa, Maha Moussa, Aditya Kavuturu…·Maria Laura Avantaggiati

This study identifies SLC25A1 as a regulator of PD-L1 and type I interferon signaling via a mitochondrial pathway, influencing tumor immune response and immunotherapy efficacy.

1 citation

humanproteomics

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Developmental BiologybioRxivPreprintJul 18, 2023

Loss of the mitochondrial carrier, SLC25A1, during embryogenesis induces a unique senescence program controlled by p53

Anna Kasprzyk-Pawelec, Mingjun Tan, Raneen Rahhal…·Maria Laura Avantaggiati

This study shows that SLC25A1 deficiency in mice causes senescence via p53-dependent pathways, leading to developmental disorders similar to human D/L-2HGA.

5 citations

mousestatistical model

𝕏 PostBluesky