Danilo Licastro

This study identifies miR-155-5p and miR-210-3p as regulators of alveolar regeneration in IPF, showing their inhibition restores epithelial repair and reverses fibrosis in mice.

This study shows ZNF687 regulates bone marrow myeloid progenitor dynamics and osteoclastogenesis, linking its loss to reduced osteoclast differentiation and increased trabecular bone mass in a mouse model.

This study identifies miR-124-3p as a promoter of alveolar epithelial transdifferentiation and shows that AAV-delivered miR-124 reduces bleomycin-induced pulmonary fibrosis in mice.

This study investigates how rare genetic variants in PD patients affect mitochondrial lipid homeostasis and neuronal excitability using patient-derived dopaminergic neurons.

This study characterizes bacterial communities in sabkha ecosystems, showing that abiotic factors drive microbial structure and that halophilic core microbiomes are resilient and culturable.

This study shows that a Muc2 mutation in Winnie mice leads to colitis-associated tumorigenesis driven by the gut microbiome and metabolome, with SPF conditions promoting severe disease and CAC.

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

This study shows that TRIM32 loss in muscle cells delays differentiation by stabilizing c-Myc mRNA, contributing to LGMDR8 pathogenesis.

This study identifies TRIM8 as a multifunctional protein involved in mitotic regulation through multi-omics analysis, showing its role in transcription, translation, and ciliary function.

This study shows that downregulating FBXO2 in human iPSC-derived neurons leads to Alzheimer's disease-like features including Aβ aggregation and tau hyperphosphorylation.

This study investigates the anti-inflammatory effects of different electrical stimuli on a 3D bioconstruct using transcriptomics and metabolomics, finding that 5V direct current shows promise.