Jorge A. Moura de Sousa

Shuttling, swapping and mixing: the rapid modular evolution of antiviral repertoires in temperate phages and their satellites

The paper identifies and characterizes defence hotspots in P2-like phages and P4-like satellites, revealing rapid modular evolution of antiviral systems through gene swapping and recombination.

Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles

This study investigates the incomplete lytic cycle of hankyphage, a Bacteroides bacteriophage, revealing defective virion formation and incomplete DNA packaging.

Logan: Planetary-Scale Genome Assembly Surveys Life's Diversity

Assembling the Sequence Read Archive (27.3 million accessions) with over 100-fold compression enables minutes-scale k-mer search and mining of enzymes, plasmids, proteins and viral reactivation.

Bacteria have numerous phage-plasmid families with conserved phage and variable plasmid gene repertoires.

The paper identifies 780 phage-plasmids across diverse bacterial phyla, groups them into 8 families based on gene repertoire similarity, and highlights their conserved phage genes and variable plasmid-like genes.

Modelling phage-bacteria interactions driving predation and horizontal gene transfer

This paper introduces eVIVALDI, a computational model to simulate phage-bacteria interactions, showing environmental structure enhances antibiotic resistance acquisition and lysogen invasion predictions.