Lauren Narcross

This study sequences and annotates the genome of Kluyveromyces marxianus Y-1190, identifies genetic factors for lactose metabolism, and develops tools for genetic manipulation to enhance its use in industrial biotechnology.

This paper improves the microbial synthesis of benzylisoquinoline alkaloids in yeast by using human monoamine oxidase A to increase selectivity and yield of (S)-reticuline and its derivatives.

The paper screens non-conventional yeasts for organic acid tolerance and engineers Pichia occidentalis to produce cis,cis-muconic acid with improved metrics compared to Saccharomyces cerevisiae.

This paper describes a yeast platform that significantly increases the production of tetrahydroisoquinoline alkaloids, enabling the synthesis of natural and unnatural derivatives.