Peter P. Zandi

This study identifies the miR-124-AMPAR pathway as a common mediator linking polygenic risks to shared behavioral changes in schizophrenia and bipolar disorder.

This study shows that bipolar disorder patient-derived neurons exhibit circadian rhythm abnormalities, with lithium non-responders showing more severe deficits that can be partially reversed by temperature entrainment.

The paper reports exome sequencing findings in bipolar disorder, identifying AKAP11 as a shared risk gene with schizophrenia through ultra-rare protein-truncating variants.

The paper introduces lncRNAKB, a comprehensive knowledgebase of 77,199 human lncRNAs with expression, conservation, and cis-eQTL data from GTEx.

The paper integrates brain DNA methylation data with GWAS to identify psychiatric risk genes, finding heritable CpG sites and methylation-trait associations linked to schizophrenia and bipolar disorder.