Author

Tess C. Leuthner

Duke UniversityORCID 0000-0001-8501-3473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Brendan F. KohrniD· 2 shared Christina M. BergemanniD· 1 shared Danielle Ferraz MelloiD· 1 shared Heather M. StapletoniD· 1 shared Ilaria R MerutkaiD· 1 shared Joel N. MeyeriD· 1 shared Kathleen A. HershbergeriD· 1 shared Kevin Stevenson· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPharmacology & Toxicology

Brendan F. KohrnORCID

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2 papers

Recent·Most cited

Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diverse Caenorhabditis elegans strains

Tess C. Leuthner, Sharon Zhang, Brendan F. Kohrn, Heather M. Stapleton, L. Ryan Baugh

The paper assesses PFAS toxicity across genetically diverse C. elegans strains, finding genetic variation influences susceptibility to specific PFAS structures.

Toxicological Sciences · Feb 22, 2025Peer-reviewedPharmacology & Toxicology

Resistance of mitochondrial DNA to chemical-induced germline mutations is independent of mitophagy in C. elegans

Tess C. Leuthner, Laura Benzing, Brendan F. Kohrn, Christina M. Bergemann, Michael J. Hipp, Kathleen A. Hershberger, Danielle Ferraz Mello, Tymofii Sokolskyi, Kevin Stevenson, Ilaria R Merutka, Sarah A. Seay, Simon G. Gregory, Scott R. Kennedy, Joel N. Meyer

This study investigates the effects of cadmium and Aflatoxin B1 on mtDNA mutagenesis in C. elegans, finding no effect on mutation frequency or spectrum despite mitophagy defects.

Nucleic Acids Research · Aug 10, 2022Peer-reviewedGenomics