Author

Grégory Fettweis

National Institutes of HealthORCID 0000-0002-6623-2264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Gordon L. HageriD· 3 shared Arpita UpadhyayaiD· 2 shared Diana A. StavrevaiD· 2 shared Franck DequiedtiD· 2 shared Kaustubh WaghiD· 2 shared Lorenzo RinaldiiD· 2 shared Manan KrishnamurthyiD· 2 shared Sohyoung KimiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Gordon L. HagerORCID

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3 papers

Recent·Most cited

Coordinated Temporal Dynamics of Glucocorticoid Receptor Binding and Chromatin Landscape Drive Transcriptional Regulation

Diana A. Stavreva, Sohyoung Kim, Saori Fujiwara, Andrew McGowan, Songjoon Baek, Lorenzo Rinaldi, Thomas A Johnson, Michele Puglia, Blagoy Blagoev, Franck Dequiedt, Gordon L. Hager, Grégory Fettweis

The paper defines a temporally resolved framework for GR-mediated gene regulation, identifying three binding classes and their functional links to transcriptional output.

bioRxiv · Apr 25, 2026 · PreprintMolecular Biology

Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers

Grégory Fettweis, Kaustubh Wagh, Diana A. Stavreva, Alba Jiménez‐Panizo, Sohyoung Kim, Michelle Lion, Andrea Alegre‐Martí, Lorenzo Rinaldi, Thomas A. Johnson, Elise Gilson, Manan Krishnamurthy, Li Wang, David A. Ball, Tatiana Karpova, Arpita Upadhyaya, , Gordon L. Hager

The paper identifies LxxLL motifs in NIPBL that regulate its interaction with MAU2 and steroid receptors, forming a ternary complex with GR to facilitate enhancer localization of cohesin.

Nucleic Acids Research · May 10, 2025Peer-reviewedMolecular Biology

The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor

Thomas A. Johnson, Grégory Fettweis, Kaustubh Wagh, Brian Almeida‐Prieto, Manan Krishnamurthy, Arpita Upadhyaya, Gordon L. Hager, Diego Álvarez de la Rosa

This study shows that GR co-expression enhances MR transcriptional activity in response to aldosterone, even without glucocorticoids.

bioRxiv · Jan 26, 2023 · PreprintMolecular Biology