Diego Álvarez de la Rosa

This study investigates how GRIN2B mutations affect NMDA receptor-BK channel coupling, showing that V618G disrupts complex formation and functional coupling, contributing to EIEE27 pathophysiology.

This study shows that GR co-expression enhances MR transcriptional activity in response to aldosterone, even without glucocorticoids.

This study shows that SGK1.1 activates the M-current in neurons and can counteract epilepsy-related mutations in Kv7.2 subunits.

This paper shows that SGK1.1 activation reduces neuronal death and gliosis after status epilepticus, acting through both M-current regulation and anti-apoptotic mechanisms.

This study shows that SGK1.1 activation reduces seizure duration and mortality in a mouse model of status epilepticus by increasing M-current in hippocampal neurons.