Author

Jonathan R. T. Lakey

University of California, IrvineORCID 0000-0001-8553-4287Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Organism:rat· 1

Frequent Co-Authors

Allison S. MoguliD· 1 shared Angela MartiniD· 1 shared Charles ChangiD· 1 shared Christie D. FowleriD· 1 shared Heshan S. PeirisiD· 1 shared Ian D. JenkinsiD· 1 shared Insung Park· 1 shared J.P. Fowler· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Allison S. MogulORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

AI Derived Therapeutic Development for the Treatment of Opioid Use Disorder

Valeria Lallai, Angela Martin, J.P. Fowler, Malia R. Bautista, Allison S. Mogul, Jinjutha E. Cheepluesak, Saman Mirzaei, Ian D. Jenkins, Jonathan R. T. Lakey, Robert Tinder, Christie D. Fowler

This paper develops an AI-based platform to identify therapeutic targets for opioid use disorder, validates a compound in animal models, and highlights challenges in drug formulation.

bioRxiv · Feb 26, 2024 · PreprintNeuroscience

Molecular and genetic regulation of pig pancreatic islet cell development

Seokho Kim, Robert L. Whitener, Heshan S. Peiris, Xueying Gu, Charles Chang, Jonathan Y. Lam, Joan Camuñas-Soler, Insung Park, Romina J. Bevacqua, Krissie Tellez, Stephen R. Quake, Jonathan R. T. Lakey, Rita Bottino, Pablo J. Ross, Seung K. Kim

This study investigates pig pancreatic islet development, identifying similarities with human islet ontogeny and uncovering signaling pathways relevant to beta-cell maturation.

Development · Feb 27, 2020Peer-reviewedDevelopmental Biology