Michael S. Levine

The paper tracks and manipulates striatal neuron activity during goal-directed learning and habit formation, finding D1+ neurons maintain stable action representations while A2A+ neurons show transient or slow reorganization.

The paper maps functional domains and subnetworks in the cortico-basal ganglia-thalamic loop in mice, revealing complex patterns of convergence and divergence.

This paper identifies a bidirectional corticoamygdala circuit that encodes and retrieves detailed reward memories in rats, showing its role in adaptive decision making.

This study shows that human neural stem cells transplanted into Huntington's disease mouse models improve behavior, reduce mutant Huntingtin, and integrate functionally into the host brain.

This study identifies CalDAG-GEFI mutations causing psychomotor symptoms and bleeding in multiple species, revealing conserved signaling deficits in striatal function.