Magdalena M. Sauvage

Intrinsic Cellular Persistent Firing Sustains Hippocampal Spatial Representations during Working Memory

The paper shows that hippocampal place cells maintain spatial information through intrinsic persistent firing via TRPC4 channels during working memory tasks in mice.

Circuit-specific reorganization of hippocampal-entorhinal-prefrontal subnetworks supports memory recall across the lifespan

The paper examines how memory recall circuits reorganize across the lifespan in mice, showing a shift from hippocampal to broader cortical networks involving the entorhinal cortex.

Phase-locking of hippocampal CA3 neurons to distal CA1 theta oscillations selectively predicts memory performance

This study shows that CA3 neuronal spiking synchronized with distal CA1 theta oscillations predicts memory performance in a non-spatial recognition task.

Inhibitory temporo-parietal effective connectivity is associated with explicit memory performance in older adults

The paper investigates effective connectivity patterns during explicit memory encoding in young and older adults, finding reduced inhibitory connectivity in older adults correlates with poorer memory performance.

Functional connectivity and information pathways in the human entorhinal-hippocampal circuitry

The paper identifies two functional pathways in the human entorhinal-hippocampal circuitry that process scene and object information differently.

Remembering the gist of an event over a lifetime depends on the hippocampus

This study shows that CA1 is necessary for gist memory retrieval regardless of memory age, while CA3 is required for memory precision in a time-dependent manner.

Recognition memory: familiarity signals increase selectively in the lateral entorhinal cortex following hippocampal lesions

This study shows that hippocampal lesions increase lateral entorhinal cortex activity during familiarity judgments, suggesting HIP modulates LEC in recognition memory.

Mutations in CalDAG-GEFI Lead to Striatal Signaling Deficits and Psychomotor Symptoms in Multiple Species Including Human

This study identifies CalDAG-GEFI mutations causing psychomotor symptoms and bleeding in multiple species, revealing conserved signaling deficits in striatal function.