Harpreet Sidhu

This study identifies PSTN Crh neurons as a key driver of alcohol drinking escalation in dependence, showing their role shifts from inhibitory to stimulatory with dependence.

This study identifies PSTN Crh neurons as drivers of alcohol drinking escalation and behavioral disinhibition in mice, independent of CRF1 signaling.

This study investigates the role of CeA CRF neurons in alcohol dependence by using chemogenetics to assess their impact on behavior and neurotransmission during withdrawal.

The paper validates the three-stage theory of addiction using single-cell whole-brain imaging in a mouse model, showing abstinence reduces brain modularity and clusters regions corresponding to each stage.

This study shows that knocking down hypocretin/orexin in rats reduces cocaine self-administration during extended access, suggesting a role in compulsive drug-taking behavior.