Max Kreifeldt

This study identifies PSTN Crh neurons as a key driver of alcohol drinking escalation in dependence, showing their role shifts from inhibitory to stimulatory with dependence.

This study shows that activating GIRK channels with GiGA1 reduces ethanol reward and intake in mice, suggesting it as a potential treatment for AUD.

This study identifies PSTN Crh neurons as drivers of alcohol drinking escalation and behavioral disinhibition in mice, independent of CRF1 signaling.

This study investigates whether ethanol's interaction with BK channel α subunit residue K361 mediates behavioral responses to alcohol in mice, finding no significant effects on ethanol-related behaviors or consumption.

This study identifies PSTN neuron subpopulations that regulate feeding initiation and consumption behaviors in mice during refeeding.

This study investigates the role of CeA CRF neurons in alcohol dependence by using chemogenetics to assess their impact on behavior and neurotransmission during withdrawal.

The paper validates the three-stage theory of addiction using single-cell whole-brain imaging in a mouse model, showing abstinence reduces brain modularity and clusters regions corresponding to each stage.