Calum C. Bain

The paper shows that monocyte-derived alveolar macrophages (mono-AMs) from different insults follow a conserved differentiation blueprint, while fetal-derived AMs show context-dependent changes.

This study shows TWEAK increases in ulcerative colitis and promotes monocyte activation through non-canonical NF-kB/STAT3 signaling in fibroblasts.

This study profiles the gastrointestinal tract over three months post-stroke in an experimental model, showing structural and microbial changes that persist chronically.

This study shows that short fixation times improve macrophage detection in immunofluorescent analysis of mouse and human tissues, without affecting other markers.

The paper identifies a novel macrophage-like population in exocrine glands sustained by ILC2-derived GM-CSF, showing conservation across species.

This study identifies three subpopulations of colonic macrophages in mice, showing they persist through inflammation and adapt transcriptionally to aid tissue repair.

This study shows that respiratory viral infection primes lung epithelial cells to enhance antigen presentation, leading to improved T cell responses to subsequent antigens.

The paper identifies CSF1 and TGFβ as key signals for synovial lining macrophage development in mice, which occurs postnatally and is monocyte-independent.

The paper identifies inflammation-associated monocytes (IAMs) in IBD and experimental colitis, showing they express ACOD1 to limit cytokine production during inflammation.