Elaine Emmerson

Fixation matters: duration in fixative prior to immunofluorescent analysis directly impacts macrophage visualisation in epithelial tissues

This study shows that short fixation times improve macrophage detection in immunofluorescent analysis of mouse and human tissues, without affecting other markers.

Unveiling a unique macrophage population in exocrine glands sustained by ILC2-derived GM-CSF

The paper identifies a novel macrophage-like population in exocrine glands sustained by ILC2-derived GM-CSF, showing conservation across species.

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair

This study identifies three subpopulations of colonic macrophages in mice, showing they persist through inflammation and adapt transcriptionally to aid tissue repair.

The synovial lining macrophage layer develops in the first weeks of life in a CSF1- and TGFβ- dependent but monocyte-independent process.

The paper identifies CSF1 and TGFβ as key signals for synovial lining macrophage development in mice, which occurs postnatally and is monocyte-independent.

Diverse progenitor cells preserve salivary gland ductal architecture after radiation induced damage

This study shows that two distinct progenitor populations in salivary glands maintain ductal architecture after radiation damage through different mechanisms.