Author

Laura J. McCulloch

Centre for Inflammation ResearchORCID 0000-0002-1396-6643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alba GraystoniD· 1 shared Alice Drake· 1 shared Anna BenrickiD· 1 shared Anne ClarkiD· 1 shared Ari WaismaniD· 1 shared Barry W. McColliD· 1 shared Belén ChanclóniD· 1 shared Bernard ThorensiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Alba GraystonORCID

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4 papers

Recent·Most cited

ImmunologyJournal of Cerebral Blood Flow & MetabolismPeer-reviewedJan 17, 2026

DYNAMIC CHANGES TO THE INTESTINAL ENVIRONMENT OCCUR THROUGHOUT RECOVERY FROM EXPERIMENTAL ISCHAEMIC STROKE

Rachel M L Martin, Isobel C. Mouat, Robert K. Whelan…·Laura J. McCulloch

This study profiles the gastrointestinal tract over three months post-stroke in an experimental model, showing structural and microbial changes that persist chronically.

3 citationstop 3%

mousebulk RNA-seq

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ImmunologyBrain Behavior and ImmunityPeer-reviewedNov 20, 2025

Cerebral ischaemic stroke results in altered mucosal IgA responses and host-commensal microbiota interactions.

Madeleine E. D. Hurry, David A Posner, Raymond Wong…·Matthew R. Hepworth

This study shows that cerebral ischaemic stroke alters mucosal IgA responses and host-commensal microbiota interactions, leading to changes in intestinal microbiota composition.

6 citations

mouseproteomics

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NeuroscienceeLifePeer-reviewedNov 6, 2023

Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's Disease

Michael J. D. Daniels, Lucas Lefèvre, Stefan Szymkowiak…·Barry W. McColl

This study investigates the sex-specific role of Cst7 in microglia in an amyloid-driven Alzheimer's Disease model, finding sexually dimorphic effects on endolysosomal function and inflammation.

30 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintApr 2, 2020

GLP-1(9-36) mediates the glucagonostatic effect of GLP-1 by promiscuous activation of the glucagon receptor

Claudia Guida, CAROLINE A. MIRANDA, Ingrid Wernstedt Asterholm…·Reshma D. Ramracheya

This paper identifies that GLP-1(9-36) inhibits glucagon secretion via the glucagon receptor, while GLP-1(7-36) uses the GLP-1 receptor, revealing distinct mechanisms for glucagon suppression.

10 citations

mouseexperimental assay

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