François Schweisguth

The paper challenges the role of Notch in Neuroblast selection during early Drosophila neurogenesis, showing that positional cues pre-pattern Neuroblast fate and that Notch stabilizes rather than initiates fate decisions.

EpiCure is a tool for curating epithelial segmentation errors in 2D movies, improving accuracy and efficiency in single-cell dynamics analysis.

This study investigates how Hedgehog signaling coordinates oscillatory atonal gene expression in Drosophila eye development.

The paper identifies NAD+ availability and redox state as constraints on developmental speed in Drosophila eye differentiation.

The paper studies symmetry breaking during lateral inhibition in Drosophila, finding that fate divergence occurs at low Sc levels without a prolonged low Sc phase and is corrected by cellular rearrangements.

The paper investigates pattern formation in the Drosophila eye using experiments and modeling, revealing a new relay model for propagating oscillations and crystal-like order through pulsatile Notch signaling.

The paper describes a coordinated epithelial-to-neural stem cell transition in Drosophila optic lobe neuroepithelium regulated by Neuralized and RhoGEF3.

This study uses optogenetic inhibition of Delta in Drosophila to show that Notch signaling exhibits digital behavior during tissue differentiation, with duration determining tissue-level responses and switch-like mechanisms at the cellular level.

The paper shows that Notch signaling and external forces, not Myosin-II, drive slow cell intercalation in Drosophila retinal glial-like cone cells.