Author

Gebremichal Gebretsadik

University of MinnesotaORCID 0000-0001-8928-852XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Anthony D. BaughniD· 2 shared Ziyi JiaiD· 2 shared Akanksha VarshneyiD· 1 shared Elise A. LamontiD· 1 shared Kenneth C. KeileriD· 1 shared Michael D. Howe· 1 shared Michelle M. ButleriD· 1 shared Muzafar Ahmad RatheriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Anthony D. BaughnORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 22, 2026

trans-Translation inhibitors that kill M. tuberculosis and pathogenic Non-tuberculous Mycobacteria have a dual mechanism of action

Akanksha Varshney, Ziyi Jia, Gebremichal Gebretsadik…·Kenneth C. Keiler

The paper identifies acylaminooxadiazole derivatives that kill mycobacteria by inhibiting trans-translation and disrupting iron homeostasis.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedDec 19, 2025

Essential Role of MHC II in the Antitubercular Efficacy of Pyrazinamide

Elise A. Lamont, Shannon Lynn Kordus, Michael D. Howe…·Anthony D. Baughn

This study shows that MHC II and CD4 T cell help are essential for pyrazinamide's antitubercular efficacy, revealing a host-mediated mechanism for its in vivo activity.

DOI 10.1128/aac.01264-25

mousebulk RNA-seq

𝕏 PostBluesky