MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
Essential Role of MHC II in the Antitubercular Efficacy of Pyrazinamide
Elise A. Lamont, Shannon Lynn Kordus, Michael D. Howe…·Anthony D. Baughn
This study shows that MHC II and CD4 T cell help are essential for pyrazinamide's antitubercular efficacy, revealing a host-mediated mechanism for its in vivo activity.
DOI 10.1128/aac.01264-25