Author

Kuan‐Yi Lu

University of North Carolina at Chapel HillORCID 0000-0002-3663-377XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Benjamin I. Morris· 1 shared Brian P. ConloniD· 1 shared Brian P. HardyiD· 1 shared Kenneth H. PearceiD· 1 shared Matthew Axtman· 1 shared Matthew J. G. EldridgeiD· 1 shared Nikki J. WagneriD· 1 shared Qingyun LiuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Benjamin I. Morris

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1 paper

Recent·Most cited

A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics

Kuan‐Yi Lu, Xiangbo Yang, Matthew J. G. Eldridge, Rongfeng Sun, Rachel T. Giorgio, Benjamin I. Morris, Nikki J. Wagner, Brian P. Hardy, Matthew Axtman, Sarah E. Rowe, Xiaodong Wang, Vance G. Fowler, Qingyun Liu, Sophie Hélaine, Kenneth H. Pearce, Brian P. Conlon

This study identifies a host-directed adjuvant, KL1, that increases intracellular bacterial energy and sensitizes persisters to antibiotics by modulating host immune responses and reducing reactive species production.

Nature Microbiology · Oct 10, 2025Peer-reviewedMicrobiology