Author
Cardiff UniversityORCID 0000-0001-8992-9120Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Victoria J. Tyrrell, Ανδρέας Ζαραγκούλιας, Wendy Powell…·Valerie B. O’Donnell
This study characterizes the lipid composition of SARS-CoV-2 envelopes from cultured strains and patient isolates, showing inflammation-induced changes and identifying lipid targets for antiviral and antithrombotic strategies.
Christopher P. Thomas, Victoria J. Tyrrell, James J. Burston…·Valerie B. O’Donnell
Alox15-deficient mice heal skin punch wounds with excess collagen, low matrix metalloproteinase activity and unresolved inflammatory gene expression; topical physiological 12/15-lipoxygenase oxylipin mixtures reduced collagen and raised collagenase activity.
Daniela O. Costa, Stuart T.O Hughes, Robert L. Jenkins…·Valerie B. O’Donnell
This study identifies IL-6's role in elevating thrombosis in RA via platelet 12-lipoxygenase-generated pro-coagulant phospholipids.